rPru p4 Peach, profilin (f421)1399
The peach allergen component Pru p4 is a profilin – an actin-binding protein and one of the important panallergens. It has high similarity with profilins from other fruits of the Rosaceae family, such as apple and cherry, and can also cross-react with profilins from pollen of unrelated plants (Artemisia vulgaris, Betula alba, Corylus avellana, P amygdalus). Pru p4 is associated with mild symptoms of oral allergy syndrome and serves as a marker for predicting non-systemic allergic reactions to peach.
Pru p4 is an important panallergen found in the flesh and skin of peach. It has a molecular weight of 14 kDa and is a eukaryotic actin-binding protein. Profilins like Pru p4 often cause cross-reactions with pollen and other plant allergens. Sensitization to Pru p4 is usually associated with mild allergy symptoms. Pru p4 is labile to high temperatures and pH, and is degraded in the gastrointestinal tract, which affects the clinical manifestations of allergy. Studies confirm its significance as a marker for assessing allergic reactions to peach and related plant allergens.
- Diagnosis of allergic reactions to peach.
- Assessment of sensitization level and allergy risk.
- Monitoring therapy effectiveness.
- Evaluation of sensitization level after allergen avoidance.
- Assessment of immune system status.
FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination of the allergen component.
Please note that the research method and reference values may vary depending on the equipment and test systems used.
- Blood sampling in the morning on an empty stomach or 4 hours after eating.
- Drinking plain still water is allowed.
- No smoking for 30 minutes before the test.
- For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.