Method

FEIA (Fluorescence Enzyme Immunoassay) – quantitative determination.

Description

rFel d2 – a cat allergen component, serum albumin found in cat blood serum, dander, and saliva. This allergen component is an important marker of sensitization in patients allergic to cats. Cat albumins share common epitopes with dog and horse albumins, which can cause cross-reactivity in some cases. Measuring the level of rFel d2 helps assess the risk of allergic reactions and possible cross-sensitization to albumins of other mammals.

Indications

Diagnosis of allergic reactions to cats.
Assessment of sensitization level and risk of allergy development.
Monitoring the effectiveness of ongoing therapy.
Evaluation of sensitization level after allergen avoidance.
Assessment of immune system status.

Preparation

Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
Drinking plain still water is allowed.
Do not smoke for 30 minutes before the test.
Children under 1 year should not eat 30-40 minutes before the test; for children aged 1-5 years, 2-3 hours fasting is recommended.

Clinical Significance

Cat albumin (Fel d2) is an important allergen component causing allergic reactions in 15-25% of patients allergic to cats. Although the main cat allergen is Fel d1, determining Fel d2 helps identify cross-reactivity with albumins of other mammals, particularly dogs, horses, and pigs. This is crucial for allergy diagnosis and selecting effective therapy, especially for allergic symptoms related to pork consumption in sensitized patients.

rFel d2 Cat, serum albumin (e220)1337

Specifications

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