Method

FEIA (Fluorescence Enzyme Immunoassay) – quantitative determination of the allergen component.

Description

rCan f2 – a dog allergen component, a lipocalin family protein found in dog dander and saliva, previously known as Can d2. This allergen component is produced in the parotid salivary gland of dogs and is transferred by saliva onto the fur. Fur, dander, and saliva are the main sources of allergens for humans. Exposure to rCan f2 can cause allergic reactions such as asthma, allergic rhinitis, rhinoconjunctivitis, and urticaria. The allergen component is stable in the environment and can remain on clothing, furniture, and other items for a long time.

Indications

Diagnosis of allergic reactions to dogs.
Assessment of sensitization level and risk of allergy development.
Monitoring the effectiveness of ongoing therapy.
Evaluation of sensitization level after allergen avoidance.
Assessment of immune system status.

Preparation

Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
Drinking plain still water is allowed.
Do not smoke for 30 minutes before the test.
For children under 1 year – do not eat 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.

Clinical Significance

rCan f2 is one of the main dog allergen components causing sensitization in about 70% of patients allergic to dogs. It shares homology with mouse urinary protein and is key for diagnosing and monitoring allergic reactions. Since hypoallergenic dog breeds do not exist, measuring rCan f2 levels helps assess the risk of allergy development and monitor its course. The allergen component can be airborne, settling on clothing and objects, increasing the risk of allergic reactions even without direct contact with the animal.

rCan f2 Dog (e102)1412

Specifications

Viewed tests

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