Method

FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination of sensitization to an allergen.

Description

Raspberry is a berry, technically a bramble fruit with nodular drupelets that easily separate from the core. It can be bright red, dark blue, yellow, or white in color. The fruits contain allergenic components Rub i1 (homolog of Bet v1) and Rub i3 (lipid transfer protein), as well as chitinase and cyclophilin. Cross-reactions with other berries of the family and fruits are known.

Indications

Diagnosis of allergic reactions to raspberry.
Assessment of sensitization level and risk of allergy development.
Monitoring therapy effectiveness.
Evaluation of sensitization level after allergen avoidance.
Assessment of immune system status.

Preparation

Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
Drinking plain still water is allowed.
Do not smoke for 30 minutes before the test.
For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.

Clinical Significance

Raspberry leaves and roots have anti-inflammatory, astringent, ophthalmic, oxytocic, and stimulating effects. They are used for gynecological issues, inflammations of the oral cavity and throat. Raspberry fruits are used for dye production, and fiber from the stems is used for paper. The test helps detect sensitization to raspberry and related allergens, which is important for accurate diagnosis and treatment of allergies.

Raspberry (f343)0583

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