Method

FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination.

Description

Mackerel (Scomber) is a genus of fish in the mackerel family, belonging to the order Perciformes. This marine fish is widely distributed from the Mediterranean and Black Seas to the Arctic and the eastern coast of America. It forms dense schools near the water surface. Mackerel meat is highly valued, but if improperly stored, it can contain histamine, which causes scombroid poisoning.

Indications

Diagnosis of allergic reactions to mackerel.
Assessment of sensitization level and risk of allergic reactions.
Monitoring the effectiveness of ongoing therapy.
Evaluation of sensitization level after allergen avoidance.
Assessment of immune system status.

Preparation

Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
Drinking plain still water is allowed.
Do not smoke for 30 minutes before the test.
For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.

Clinical Significance

Mackerel and other family members decompose quickly and, if improperly stored, may contain histamine, causing scombroid poisoning. Sensitivity to mackerel is observed in a significant portion of patients allergic to fish. The clinical sensitivity and specificity of the Pharmacia CAP System™ f206 Mackerel test are 86% and 90%, respectively, making it important for diagnosing and monitoring allergic reactions.

Mackerel (f206)0854

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