Method

FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination of allergen-specific antibodies.

Description

Dates (Phoenix dactylifera L.) are popular fruits from southern countries, rich in nutrients and trace elements such as boron, cobalt, copper, fluorine, magnesium, manganese, selenium, zinc, and potassium. They are beneficial for the cardiovascular and nervous systems, normalize gastrointestinal function, and improve memory and sleep. However, dates are potential allergens that can cause allergic reactions in sensitive individuals.

Indications

Diagnosis of allergic reactions to dates.
Assessment of sensitization level and risk of allergy development.
Monitoring therapy effectiveness.
Evaluation of sensitization level after allergen avoidance.
Assessment of immune system status.

Preparation

Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
Drinking plain still water is allowed.
Do not smoke for 30 minutes before the test.
For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.

Clinical Significance

Two main groups of allergenic proteins have been identified in dates. The first is the profilin NPHO D2, also found in date palm pollen, to which about 10% of Ukrainian patients are sensitive. Sensitization is associated with cross-reactions to pollen from various plants, including birch, timothy grass, and others. The second potential allergen is the lipid transfer protein (LTP), which can cause severe allergic reactions, including anaphylaxis.

Drying dates reduces their allergenicity but does not eliminate it completely. Fungal contamination and sulfites used as preservatives play an important role in allergy development. Contact with dates or inhalation of their vapor can also trigger allergic reactions. Tyramine contained in dates may cause migraines in sensitive individuals.

Date (f289)1592

Specifications

Viewed tests

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