Rye (Secale cereale) is one of the most common and resilient cereals, widely used in the food industry, baking, and other sectors. However, rye is a frequent cause of allergic reactions, especially among the European population where rye bread consumption is very common. Inhalation of rye flour can cause respiratory symptoms, allergic reactions, and even anaphylaxis.
Rye allergen can cause a wide range of symptoms: from classic food allergies to occupational rhinitis, asthma, contact dermatitis, and even anaphylaxis. The main allergenic component is Sec c38 – an α-amylase inhibitor. Rye shows cross-reactivity with other cereals, particularly wheat, barley, as well as allergens from poppy, hazelnut, soy, fungal α-amylases, and pollen from grasses and trees. Sensitized individuals are advised to avoid rye flour in their diet and to pay attention to product labeling due to gluten content.
FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination of allergen level.
Please note that the research method and reference values may vary depending on the equipment and test systems used.