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The peach allergen component Pru p1 is a PR-10 family protein homologous to the major birch pollen allergen Bet v1. Sensitization to Pru p1 is common in regions with high birch pollen exposure and typically causes oral allergy syndrome symptoms such as itching and irritation of the oral mucosa, as well as angioneurotic edema of the lips, tongue, or throat. Pru p1 is heat- and enzyme-labile and may cross-react with grass pollen, alder pollen, and other fruits of the Rosaceae family (apple, apricot, pear, cherry). This allergen component is an important diagnostic marker for allergy to Rosaceae fruits.
Pru p1 is a thermolabile protein that is easily destroyed by heating and digestion. It has high cross-reactivity with birch pollen (Bet v1) and is associated with birch pollen allergy, often presenting with oral allergy syndrome symptoms. Co-sensitization with alder and grass pollen allergies is common, related to pollen-food allergy syndrome (PFAS). Pru p1 also cross-reacts with other Rosaceae fruits, hazelnut, carrot, and celery. Due to its high homology with Bet v1 and Mal d1 (apple) proteins, this test helps determine the risk of cross-reactive allergic reactions and supports accurate allergy diagnosis.
FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination.
Please note that the research method and reference values may vary depending on the equipment and test systems used.