rPol d5 Wasp venom polistine (i210)

Homologs of antigen 5 are known from various wasps, hornets, and paper wasps. Sequence similarity of about 98% is observed between P. dominulus and P. gallicus, which are European Polistes species. This similarity decreases when comparing Polistes from Europe and the USA, and even more so when antigen 5 is compared across different genera. For example, antigen 5 shows 69% and 60% sequence identity with homologous proteins from Dolichovespula maculata and Polistes annularis, respectively. Structural similarity between proteins suggests, but does not guarantee, clinical cross-reactivity in sensitive patients.

Antigen 5 has also been detected in the venoms of various ants, with significant variations demonstrated in protein sequence similarity to homologous proteins of different Vespidae species.

• Diagnosis of allergic reactions.
• Assessment of sensitization level and risk of allergy development.
• Monitoring therapy effectiveness.
• Evaluation of sensitization level after allergen avoidance.
• Assessment of immune system status.

FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination.

• Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
• Drinking plain still water is allowed.
• Do not smoke for 30 minutes before the test.
• For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.