The allergen component Phl p1, derived from timothy grass pollen (Phleum pratense), is one of the main molecular allergens of group 1 grass pollens. It is a glycosylated protein with a molecular weight of about 30 kDa, which acts as a cross-reactive antigen in many grass species and corn. Phl p1 belongs to the beta-expansin subclass, proteins responsible for loosening the plant cell wall.
Phl p1 is the main allergen component of timothy grass, identified in over 90% of patients allergic to grass pollen. It has high cross-reactivity among grasses from temperate and tropical regions. This molecular allergen initiates sensitization in most patients with pediatric allergic rhinitis and is a key marker for allergy diagnosis and therapy. The use of recombinant allergens such as Phl p1 improves diagnostic accuracy and allows assessment of specific IgE response in patients.
FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination.
Please note that the research method and reference values may vary depending on the equipment and test systems used.