Rheumatoid factor IgA (RF IgA) are autoantibodies directed against the Fc fragment of IgG. Determining RF IgA in blood serum helps predict erosive damage to joint cartilage in rheumatoid arthritis (RA). Combined with antibodies to cyclic citrullinated peptide (anti-CCP), this test allows detection of the disease at early preclinical stages and is used for screening individuals at risk.
Rheumatoid factors (RF) are autoantibodies that can be present in various autoimmune diseases, including rheumatoid arthritis, Sjögren's syndrome, systemic lupus erythematosus, and others. The IgA subclass of RF is an important diagnostic marker that complements information about disease activity and severity. The presence of RF IgA combined with other RF subclasses and anti-CCP antibodies is 100% specific for rheumatoid arthritis, improving diagnosis, differential diagnosis, and treatment monitoring.
FEIA (Fluorescence Enzyme Immunoassay) – quantitative determination of IgA antibodies to rheumatoid factor.
Please note that the research method and reference values may vary depending on the equipment and test systems used.