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rAsp f6 Aspergillus fumigatus (m222)

1596
1290.001226.00 ₴
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Asp f6 is a phylogenetically conserved mitochondrial manganese superoxide dismutase (MnSOD) derived from the fungus Aspergillus fumigatus. This fungus is a common cause of allergic fungal respiratory diseases, such as severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis. Sensitization to Asp f6 is mainly found in patients with ABPA, making this marker important for diagnosing this condition. Cross-reactivity of Asp f6 is observed in atopic dermatitis due to sensitization to similar proteins.

Asp f6 is a 26.5 kDa protein that forms homotetramers and has proven allergenicity. It performs a detoxifying function inside cells, protecting the fungus from oxidative stress. Sensitization to Asp f6 is an important diagnostic marker for allergic bronchopulmonary aspergillosis. Cross-reactivity with other MnSODs partially explains the immune response characteristics in atopic conditions.

  • Diagnosis of allergic reactions.
  • Assessment of sensitization level and risk of allergy development.
  • Monitoring therapy effectiveness.
  • Evaluation of sensitization level after allergen avoidance.
  • Assessment of immune system status.

FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination of sensitization level.

Please note that the research method and reference values may vary depending on the equipment and test systems used.

  • Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
  • Drinking plain still water is allowed.
  • Do not smoke for 30 minutes before the test.
  • For children under 1 year – refrain from eating for 30-40 minutes before the test; for children aged 1-5 years – 2-3 hours.

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