The test detects sensitization to Ana o3 – a 2S albumin, the major storage protein of cashew nuts. Ana o3 is a key marker of cashew allergy, associated with a high risk of severe allergic reactions, including anaphylaxis. This protein is resistant to heat treatment and digestion, which contributes to its high allergenicity.
Patients allergic to cashew nuts have an increased risk of severe allergic reactions, often more severe than peanut allergy. Sensitization to Ana o3 indicates primary cashew allergy and is associated with the risk of systemic reactions even with minimal allergen exposure. The test helps identify the high allergenic potential of the 2S albumin, which is resistant to various processing methods. The results are important for treatment planning, allergen avoidance, and assessing cross-reactivity with other nuts and seeds.
FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination of specific IgE to Ana o3 cashew protein.
Please note that the research method and reference values may vary depending on the equipment and test systems used.