Bermuda grass (Cynodon dactylon) is widespread in warm climatic regions of the world. Its pollen contains at least 12 IgE-binding proteins. Cyn d1 is the main allergenic component of this grass and belongs to the group of expansin proteins with a molecular weight of 32-34 kDa.
Expansins are proteins that facilitate the loosening of plant cell walls and are important allergens of group 1 grasses. Cyn d1 is a member of this group, and about 95% of patients allergic to grass pollen are sensitized to allergens of this group. The sensitization rate to Cyn d1 among patients allergic to Bermuda grass ranges from 76-100%.
This allergenic component shows high cross-reactivity with other grasses of the Chloridoideae subfamily, such as Buffalo, Windmill, and Grama grasses. Cyn d1 is immunologically distinct from Phl p1 of Timothy grass, making it a valuable marker for diagnosing sensitization specifically to Bermuda grass.
FEIA (Fluorescence Enzyme Immunoassay) – a fluorescent enzyme immunoassay for quantitative determination of sensitization levels.
Please note that the research method and reference values may vary depending on the equipment and test systems used.