Botrytis cinerea is a common necrotrophic phytopathogenic fungus that causes gray mold on more than 200 plant species in temperate and subtropical regions. It is responsible for significant economic losses due to crop spoilage before and after harvest. The fungus has allergenic potential, causing allergic rhinitis, asthma, and hypersensitivity pneumonitis, especially in horticulture and viticulture workers. A distinctive feature of B. cinerea is its resistance to pesticides and its ability to form sclerotia that survive in the environment for years.
Botrytis cinerea is one of the main allergens among mold fungi causing severe allergic respiratory diseases, including fungal asthma and hypersensitivity pneumonitis. Despite its low airborne prevalence, the fungus has high sensitizing activity. Carbohydrate components of the fungal cell wall, such as β-glucan and chitin, can enhance immune system allergic reactions. Determining the sensitization level to B. cinerea aids in diagnosis, monitoring, and treatment of allergy conditions related to this fungus.
FEIA (Fluorescence Enzyme Immunoassay) is a fluorescent enzyme immunoassay that allows quantitative determination of sensitization levels to allergens.
Please note that the research method and reference values may vary depending on the equipment and test systems used.