1. All tests
  2. Allergy Diagnostics
  3. Immunoglobulin E (total), quantitative determination

Immunoglobulin E (total), quantitative determination

0435
841.00 ₴
Available

Immunoglobulin E (IgE) is responsible for the development of allergic reactions. It is produced locally, mainly in the submucosal layer of tissues that come into contact with the external environment. It does not cross the placental barrier. The half-life in serum is 3-5 days and 14 days on the membranes of mast cells and basophils. In addition to its role in type I allergic reactions, IgE also participates in protective anti-helminth immunity.

Immunoglobulin E (IgE) is a marker of immediate-type allergy and helminth infections. Its concentration in blood serum is less than 0.001% of all immunoglobulins and is produced by plasma cells of various organs. IgE mediates interaction with allergens on the surface of basophils and mast cells, leading to the release of histamine and other allergy mediators. IgE levels increase from birth to adolescence and may decrease in old age. Detection of IgE aids in the diagnosis of allergic diseases and helminth infections.

  • Suspected allergic diseases: bronchial asthma, pollinosis, atopic dermatitis, eczema, food and drug allergies.
  • Suspected helminth infections.
  • Assessment of the risk of developing allergic diseases in children with a family history of allergic pathology.

FEIA (Fluorescent Enzyme Immunoassay) – quantitative determination.

Please note that the research method and reference values may vary depending on the equipment and test systems used.

  • Blood should be drawn in the morning on an empty stomach or 8 hours after eating.
  • Drinking plain still water is allowed.
  • Do not smoke for 3 hours before the test.
  • Avoid physical exertion and psycho-emotional stress for 30 minutes before the test.
  • For children under 1 year – do not feed 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.
  • Avoid taking medications 12 hours before the test, with doctor's approval.

Viewed tests