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Histamine

0357
2992.00 ₴
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Histamine is a biologically active substance, an inflammation mediator found in various living organisms. It is released by specialized mast cells upon activation, often during an allergic reaction, and plays a key role in the development of allergy symptoms and inflammatory processes.

Histamine is a key mediator of allergic reactions, causing itching, redness, hives, vomiting, fainting, and even anaphylactic shock. Elevated histamine levels indicate mast cell activation, which is important for diagnosing allergic conditions and certain tumors. The test helps confirm anaphylactic shock and assess the degree of mast cell activation. Plasma histamine levels are transient and can rise within 5–10 minutes after symptom onset, making the timing of sample collection critically important.

  • Confirmation of anaphylactic reaction.
  • Assessment of mast cell activation.
  • Diagnosis of tumors: mastocytoma, polycythemia vera, chronic myeloid leukemia, carcinoids.

RIA (Radio-Immunoassay) – quantitative determination.

Please note that the research method and reference values may vary depending on the equipment and test systems used.

  • Blood should be drawn in the morning on an empty stomach or 12 hours after eating.
  • Drinking plain still water is allowed.
  • Do not smoke for 30 minutes before the test.
  • For children under 1 year – refrain from eating 30-40 minutes before the test; for children aged 1-5 years – 2-3 hours.
  • Exclude alcohol, nicotine, coffee, tea, cocoa, and foods high in histamine (wine, cheese, sauerkraut, avocado, bananas, canned products) for 48 hours before the test.
  • Avoid physical exertion and emotional stress for 24 hours before the test.
  • Avoid taking medications for 24 hours before the test, subject to doctor’s approval.

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