Grapes (f259)0295
Grape (Vitis vinifera) belongs to the family Vitiaceae, subfamily Ampelideae. The composition of the pulp of ripe fruits depends on the variety, climate, physicochemical soil characteristics, and farming methods. The analysis determines sensitization to the main allergenic components of grape, including the lipid transfer protein Vit v1, profilin Vit v4, chitinase-like protein Vit v5, thaumatin-like protein Vit v Thaumatin, and beta-1,3-glucanase.
FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination.
- Diagnosis of allergic reactions to grape.
- Assessment of sensitization level and risk of allergy development.
- Monitoring therapy effectiveness.
- Evaluation of sensitization level after allergen avoidance.
- Assessment of immune system status.
- Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
- Drinking plain still water is allowed.
- Do not smoke for 30 minutes before the test.
- For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.
Grape contains important allergenic components, notably the lipid transfer protein Vit v1, which causes sensitization in 70-100% of patients allergic to grape. This protein is resistant to gastric digestion and has high homology with peach LTP, explaining cross-reactions with fruits of the Rosaceae family. Cross-reactions are also possible with other foods containing lipid transfer proteins, such as peach, cherry, apricot, banana, kiwi, and others. Other allergenic components, like thaumatin-like protein, have less clinical significance. This test helps identify sensitization and avoid adverse reactions.