This test determines the body's sensitization to major fruit allergens: banana, orange, green apple, and peach. The analysis allows detection of the level of IgE-mediated hypersensitivity, which is important for diagnosing allergic reactions and planning further therapy.
The main allergen component of banana is the protein Mus a1, which belongs to profilins and is associated with cross-sensitization to grass, birch pollen, orange, and other fruits. Other banana proteins (Mus a2, Mus a5, Mus a6) are linked to latex allergy, occurring in 45% of patients.
The allergen Mus a3 is a lipid transfer protein that is heat-stable and can cause severe anaphylactic reactions. Similar proteins are present in peach, apple, orange, and other fruits of the Rosaceae family.
In orange, heat-stable proteins Cit s1 and Cit s3 have been identified, which cause systemic allergic reactions, as well as the profilin Cit s2, responsible for oral allergy syndrome. Cross-reactions with other citrus fruits and peach are also possible.
In green apples, the main allergen component is the protein Mal d1, which accumulates during fruit storage and triggers allergic reactions.
Peach is one of the leading allergens among Rosaceae fruits, especially in the Mediterranean region, where sensitization to the protein Pru p3 often leads to severe allergic manifestations.
FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination.
Please note that the research method and reference values may vary depending on the equipment and test systems used.