Dates (Phoenix dactylifera L.) are popular fruits from southern countries, rich in nutrients and trace elements such as boron, cobalt, copper, fluorine, magnesium, manganese, selenium, zinc, and potassium. They are beneficial for the cardiovascular and nervous systems, normalize gastrointestinal function, and improve memory and sleep. However, dates are potential allergens that can cause allergic reactions in sensitive individuals.
Two main groups of allergenic proteins have been identified in dates. The first is the profilin NPHO D2, also found in date palm pollen, to which about 10% of Ukrainian patients are sensitive. Sensitization is associated with cross-reactions to pollen from various plants, including birch, timothy grass, and others. The second potential allergen is the lipid transfer protein (LTP), which can cause severe allergic reactions, including anaphylaxis.
Drying dates reduces their allergenicity but does not eliminate it completely. Fungal contamination and sulfites used as preservatives play an important role in allergy development. Contact with dates or inhalation of their vapor can also trigger allergic reactions. Tyramine contained in dates may cause migraines in sensitive individuals.
FEIA (Fluorescence Enzyme Immunoassay, ImmunoCAP (Solid-phase Immunofluorescence)) – quantitative determination of allergen-specific antibodies.
Please note that the research method and reference values may vary depending on the equipment and test systems used.