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  3. Yeast fungi Malassezia spp. (m227)

Yeast fungi Malassezia spp. (m227)

1617
1254.001191.00 ₴
Available

Fungal species of the genus Malassezia are part of the normal microbiome of healthy human skin. The most common species are M. sympodialis, M. globosa, M. restricta. A link has been found between hypersensitivity to specific Malassezia allergens and atopic dermatitis and allergic respiratory diseases. More than 30 specific Malassezia allergens have been identified, which show cross-reactivity with allergens from other fungi.

About 20 Malassezia spp. allergens are recognized by WHO/IUIS. Studied molecular allergens of M. sympodialis (Mala s 5, 6, 10, 14) show similarity to human proteins. Sensitization is associated with bronchial asthma, allergic rhinitis, atopic eczema. Mal f1 triggers the TH22/TH17 pathway, explaining reduced effectiveness of some therapies. MGL_1304 causes strong allergic reactions in patients with allergic dermatitis and cholinergic urticaria. Skin barrier defects enhance sensitization to these allergens.

  • Diagnosis of allergic reactions.
  • Assessment of sensitization level and risk of allergy development.
  • Monitoring therapy effectiveness.
  • Assessment of sensitization level after allergen avoidance.
  • Evaluation of immune system status.

FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination.

Please note that the research method and reference values may vary depending on the equipment and test systems used.

  • Blood should be drawn in the morning on an empty stomach or 4 hours after eating.
  • Drinking plain still water is allowed.
  • Do not smoke for 30 minutes before the test.
  • For children under 1 year – no food 30-40 minutes before the test; for children 1-5 years – 2-3 hours fasting.

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