Candida albicans (C. albicans) – unicellular yeasts that are opportunistic pathogens, especially in people with weakened immune systems. They can grow in three forms: yeast, pseudohyphae, and true hyphae. The cell wall consists of mannoproteins, β-glucans, and chitin. This fungus is part of the normal human microbiota and can cause allergic reactions, including asthma, atopic dermatitis, and skin symptoms in sensitized individuals. The main allergenic components are Cand a1 and Cand a3, with cross-reactivity to molds and other yeasts.
Recognized allergens of Candida albicans include Cand a1 (alcohol dehydrogenase) and Cand a3 (peroxisomal membrane protein), officially confirmed by WHO/IUIS. There are also several other allergens with varying molecular weights that may cause cross-reactivity with other fungal and yeast allergens. This is important for the diagnosis and treatment of allergies related to C. albicans.
FEIA (Fluorescence Enzyme Immunoassay), ImmunoCAP (Solid-phase Immunofluorescence) – quantitative determination.
Please note that the research method and reference values may vary depending on the equipment and test systems used.